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KMID : 0357819930170020008
Korean Journal of Legal Medicine
1993 Volume.17 No. 2 p.8 ~ p.19
Analysis of Family Relationship Based on the DNA fingerprints using pV47-2 Multilocus Minisatellite Probe.


Abstract
Human DNA fingerprints using multiocus minisatellite probe pV47-2 are analyzed to investigate their mutation rate and band sharing rates between paternal parent and child, maternal parent and child, and among sibs within each family in 106
individuals
consisting of 33 Korea families. The estimate of mutation rate is 0.1397 per individual or 0.0113 per band. The band sharing rates of fathers and mothers with their children do not differ significantly, their overall mean values are 53.1% and
57.1%,
respectively. The average observed rate for parent-child band sharing is 55.45%, whereas its expected rate is 56.97%, which is distributed as binominal at 5% level of significance. The average band sharing rate between sibs is ranged from 26 to
87%(mean
: 58.87%), which is also distributed as binominal at 5% level of significance. Though family relationships assessed from the band sharing rates between parent and child, and between members of both parents and child, these rates are prospective
to
be
successfuly applied for distinguishing family relationship.
KEYWORD
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